Since the Covid-19 pandemic hit the world more than two years ago, more than 4.5 billion people worldwide have been fully vaccinated. Now more and more people are worried about the effects of spiky proteins contained in vaccines on the body. Is spike protein actually the cause of their long-term Covid syndrome?
The spike protein, also known as protein S, is the largest structural protein in SARS-CoV-2 virus that causes Covid-19. It is a large structure that protrudes from the surface of the virus.
When the pandemic first began to spread, people’s understanding of spike protein was very limited. Spike protein was thought to play only the role of binding to ACE (an enzyme that converts angiotensin) receptors and helping the virus to attack cells. However, scientists have slowly discovered that the effects of this protein are multiple and that it interacts with cells other than ACE2 receptors.
8 ways protein spikes harm the body
Over the more than two years of the Covid-19 pandemic, many studies have analyzed the threat posed by spiky protein from a variety of perspectives and found it harmful to the human body in several ways, including:
1. Damage to lung cells (including pulmonary alveoli and pulmonary endothelial cells);
2. Damage to mitochondria and DNA structures;
3. Damage to cardiovascular cells;
4. Increased risk of blood clots;
5. Damage to brain cells;
6. Stimulating inflammation;
7. Suppression of immunity;
8. Increasing the risk of cancer
We will go into the details of each of these points.
With proteins can affect multiple organs
When the virus enters the human body, spiky proteins will affect multiple organs in different ways. Studies have shown that many organ cells can be affected by spiky proteins, such as those in the heart, brain, and cardiovascular system. In addition, an article published in 2021 in the bioRxiv reprint repository states that S proteins cause:
- catalytic receptors type 1 in the kidneys increase the tissue of kidney cells, and this type of receptor can host the virus, making the kidneys more susceptible to viral infection
- cells in the small intestine to stimulate a large amount of L-SIGN (intracellular adhesion molecules specific for liver / lymph nodes-3 grabbing non-integrin) receptors to defend against pathogens. However, once a large amount of adhesions on the surface of small intestinal cells bind to viruses, this will make the small intestine more susceptible to viral infection. A similar situation can occur in other organs, such as the kidneys and duodenum
- increase in the amount of DC-SIGN (Dendritic Cell-Specific Intercellular Adhesion Molecule-3-Grabbing Non-integrin) receptors in the lungs, which may cause inflammatory symptoms in the lungs
In addition, spiky proteins can cause varying degrees of oxidation of organs, leading to premature death of multiple cells and bringing the body into a hyperoxidized state, which can further increase the risk of cancer.
A new study published in the Journal of the American Heart Association found that chic proteins have a direct effect on lung function.
When spiky proteins are present in the human body, the walls of the lung alveolar cells will begin to thicken and harden, and lung function will decline. Furthermore, proteins will also affect the mitochondrial functions of lung cells, which are the body’s energy base.
Spike proteins damage mitochondria, probably causing long-lasting Covid
Under normal circumstances, the mitochondria in cells are tubular “cell power plants” responsible for energy synthesis.
When lung alveolar cells or endothelial cells are stimulated with spiky proteins, the mitochondrial structure will change dramatically and become highly fragmented, and the number of tubular mitochondria will be greatly reduced. Because most cells in the alveoli or endothelial tissue are severely damaged in shape and function, they will not be able to produce energy efficiently, which is likely to cause the cells to enter a state of premature decay and death.
Therefore, it is hypothesized that prolonged Covid-19 syndrome could be caused by mitochondrial damage. Fatigue is known to be one of the main symptoms of chronic Covid-19 syndrome. The reason for this may be the fact that the cells in some important organs and tissues are not completely dead, but their mitochondrial functions are severely damaged, which is why the cells have entered a state of premature decay and death. This results in a lack of energy and makes a person particularly prone to fatigue.
Mitochondrial damage in different cells can also cause different symptoms. If the mitochondrial functions of the lung cells are impaired, then the functions of the lung alveoli to expand and contract will be impaired, oxygen absorption will be poor, and the body’s metabolic levels will also be reduced. It also makes a person more prone to fatigue.
Spike proteins damage the cardiovascular system and cause blood clots
The heart and myocardial systems contain a very important type of cells: pericardial cells, which are outside the endothelial cells of blood vessels and are usually combined with endothelial cells to help blood vessels in transmitting various signals.
A study published in Clinical Science found that when the SARS-CoV-2 virus enters the body, spiky proteins will bind to CD147 receptors on the surface of pericardial cells, making them more likely to detach from the surface of endothelial cells. . This will affect some of the endothelial cell functions and accelerate vascular wall cell death.
In addition, spiky proteins themselves can directly stimulate pericardial cells to produce more pro-inflammatory factors that can damage the myocardium and cause blood clots.
Spiky proteins can also cause thrombosis. Another experiment published in the BioRxiv preprint repository investigated how platelets change after stimulation with spiky proteins.
The experiment compared the chic protein of the SARS-CoV-2 virus with another viral protein called VSV (vesicular stomatitis virus) and found that more platelets were induced to coagulate in the presence of spiky proteins.
Spike proteins reduce immunity
When the human body is infected with viruses, spike proteins activate the immune system to respond to this external crisis, including innate immune system, acquired immune system and cytokines released after the immune system is stimulated, so the impact of spike protein on the immune system is also extensive . This is also shown in a paper published in the journal Leukemia.
For example, there are 11 types of charge-like receptors in the innate immune system, and the seventh type of these toll-like receptors can recognize RNA single-stranded viruses. The mRNA (Messenger RNA) that enters the body after Covid-19 infection or vaccination is also single-stranded, and immune cells will recognize and attack the RNA of the virus. In the presence of spiky proteins, the amount of toll-like receptor expression may increase in response to a viral attack, and complementary immune cells may release more interferon in response to different viral variants.
If the amount of viral chic proteins in the body is too high, they can over-activate interferon expression, which can even trigger the body’s immune system to attack its own cells.
Do vaccine proteins stay in the body?
As we know, Covid-19 vaccines have incorporated an expression mechanism for viral spike proteins, allowing our immune system to recognize the virus. However, how long do vaccine proteins stay in the body?
The spike proteins are divided into two parts: S1 and S2, where S1 remains in the blood and S2 is bound to cell membranes.
A study published in Clinical Infectious Diseases found that S1 proteins will appear in humans soon after the first dose of Moderna, and that some people will still have intact spike proteins two weeks after the first dose of the vaccine.
However, other proteins in the virus, such as nucleocapsid proteins, were not present because they were not included in the vaccine.
The discovery that intact spike proteins were still present in human bodies two weeks after vaccination was beyond expectations.
Another study published in the Journal of Immunology showed that S2 proteins can still be detected four months after the second dose of Pfizer.
However, the damage of spiky proteins is related to their amount. All of the listed side effects are based on in vitro studies and animal models, and relatively serious damage occurred only when the amounts of spike protein were large.
If the viral mRNA in the vaccine appeared only in small amounts in the muscles and did not enter the blood or organs in large quantities, then these serious side effects would not occur.
How to get rid of spike proteins from the body
If prolonged Covid-19 syndrome develops after infection or vaccination, what medications can be used to expel spiky proteins and improve symptoms? The World Health Council (WCH) has made several recommendations for nutrients and medicines.
1. Nutrients that can help improve symptoms:
These are all nutrients that help boost the immune system, thus helping the body eliminate protein.
2. Common medications used to improve symptoms:
Mast cell stabilizers
3. Plant extracts
Some herbal extracts in nature can also help detoxify the body, including:
Pine needle extract
Dandelion leaf extract
Some of these ingredients, such as shikimic acid contained in pine needles, have antioxidant properties that can reduce oxidized free radicals in the body and provide a detoxifying effect.
The above drugs are not drugs, but they can help boost immunity and balance the body’s immune mechanism, which is helpful in the overall fight against the virus.
It is important to emphasize that the situation is different for everyone. Therefore, it is necessary to talk to your doctor before taking medications recommended by WCH, to make sure they are appropriate.
World Health Council: A Practical Approach to Health after a Covid-19 Sting